Enhanced frequency of neutrophils and inflammatory monocytes and diminished numbers of T and B cells in active pulmonary tuberculosis

نویسندگان

  • N Pavan Kumar
  • Luke Elizabeth Hanna
  • MS Jawahar
  • VV Banu Rekha
  • R Sridhar
  • Thomas B Nutman
  • S Subash Babu
چکیده

Background Mycobacterium tuberculosis (M.tb) infects nearly 2 billion people worldwide. Effective immunity against M.tb infection requires co-ordinated responses from both innate and adaptive arms of immunity. To elucidate the immune responses important both in control of infection and in extra-pulmonary dissemination, we examined frequency and/or absolute numbers of T, B and NK cells, dendritic cells and other leucocyte populations in active tuberculosis patients.

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عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2012